SCNM1 Polyclonal Antibody
Catalogue Numbers: BS60558-50, BS60558-100
Sizes: 50µl, 100µl
Alternative Name: Sodium channel modifier 1; SCNM1
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q9BWG6
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. SCNM1 (sodium channel modifier 1) is a 230 amino acid protein that contains one matrin-type zinc finger. Localized to the nucleus, SCNM1 is thought to function as an RNA splicing factor that may modify the expression of sodium channel-related proteins. SCNM1 exists as two alternatively spliced isoforms that are encoded by a gene which maps to chromosome 1. Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and making up 8% of the human genome. Several disorders, including Stickler syndrome, Parkinsons Disease, Gaucher disease, malignant melanoma and Usher syndrome, are caused by defects in genes that localize to chromosome 1.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: SCNM1 polyclonal antibody detects endogenous levels of SCNM1 protein.
Bioworld Molecular Weight: ~ 26 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of SCNM1 polyclonal antibody at 1:500 dilution
Lane 1: Hela whole cell lysate
Lane 2: Raw264.7 whole cell lysate
Lane 3: H9C2 whole cell lysate
Immunogen: A synthetic peptide corresponding to residues in Human SCNM1
Conjugate: Unconjugated
Modification: Unmodified