SCNN1G Polyclonal Antibody Sizes: 50µl, 100µl Catalogue Numbers: BS91212-50, BS91212-100 Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Swiss-Prot: P51170(Human) Q9WU39(Mouse) P37091(Rat) Host: Rabbit Reactivity: Human, Mouse, Rat Applications: WB, ICC IHC FC All Applications: WB:1:500-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100 Background: Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus.
Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. Purification and Purity: Protein affinity purified. Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles. Specificity: SCNN1G polyclonal antibody detects endogenous levels of SCNN1G protein. Bioworld Molecular Weight: 74 kDa Note: For research use only, not for use in diagnostic procedure. Extra Notes: Western blot analysis of SCNN1G on A431 cell lysate using anti-SCNN1G antibody at 1/1,000 dilution., ICC staining SCNN1G in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. Alternative Name: ENaCG, Gamma-ENaC, SCNN1G, Amiloride sensitive epithelial sodium channel gamma subunit, Amiloride sensitive sodium channel subunit gamma, Amiloride-sensitive sodium channel subunit gamma, BESC3, ENaC gamma subunit, ENaCG, ENaCgamma, Epithelial Na(+) channel subunit gamma, Epithelial Na+ channel subunit gamma, Gamma ENaC, Gamma NaCH, Gamma-ENaC, Gamma-NaCH, Nonvoltage gated sodium channel 1 subunit gamma, Nonvoltage-gated sodium channel 1 subunit gamma, PHA 1, PHA1, SCNEG, SCNN 1G, SCNN1G, SCNNG, Sodium channel epithelial 1 gamma subunit, Sodium channel non voltage gated 1 gamma subunit, Sodium channel nonvoltage gated 1 gamma, Immunogen: Recombinant protein within human SCNN1G aa 250-350. Conjugate: Unconjugated Modification: Unmodified