Product Description

SCP2 Polyclonal Antibody

Catalogue Numbers: BS67127-50, BS67127-100

Sizes: 50µl, 100µl

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: Q9BX26

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB (1/500 - 1/2000)

Background: Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. Plays a role in the assembly of synaptonemal complexes. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility. Required for insertion of SYCP3 into synaptonemal complexes. May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of SCP2 protein.

Extra Notes: Western blot analysis of SCP2 expression in HEK293T (A), H1792 (B), SGC7901 (C) whole cell lysates.

Bioworld Molecular Weight: ~ 165 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: SCP2; Synaptonemal complex protein 2; SCP-2; Synaptonemal complex lateral element protein; hsSCP2

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human SCP2. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified