SCRN2 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-52745-60, E-AB-52745-120, E-AB-52745-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: SCRN2
Target Synonym: scrn2; SCRN2; Secernin 2; Secernin-2; Ses2
Research Areas: Cell Biology
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q96FV2
Background: The SCRN (Secernin) gene family has three vertebrate paralogs, i.e. SCRN1, SCRN2 and SCRN3, which are closely linked to human HOXA, HOXB and HOXD cluster, respectively. SCRN2 (secernin-2) is a 425 amino acid protein that belongs to the peptidase C69 family and the Secernin subfamily. Vertebrate SCRN genes showed a topology of the form (A)(BC), i.e. (Hsa2 Hsa7)(Hsa17), with SCRN2 falling outside the SCRN3–SCRN1 cluster. The SCRN2 gene is conserved in dog, cow, mouse, rat and zebrafish, and maps to human chromosome 17q21.32. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1, 200 genes. Chromosome 17 is linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.
Concentration: 0.84 mg/mL
Immunogen: Fusion protein of human SCRN2
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Calculated MW: 47 kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only