Product Description

SDCCAG8 Polyclonal Antibody

Catalogue Numbers: BS61055-50, BS61055-100

Sizes: 50µl, 100µl

Alternative Name: Serologically defined colon cancer antigen 8; Antigen NY-CO-8; Centrosomal colon cancer autoantigen protein; hCCCAP; SDCCAG8; CCCAP; NPHP10

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q86SQ7

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: SDCCAG8 (serologically defined colon cancer antigen 8), also known as CCCAP (centrosomal colon cancer autoantigen protein), HSPC085 or NY-CO-8, is a 713 amino acid cytoplasmic protein that is expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa and renal cancer tumors. Existing as a homodimer, SDCCAG8 localizes to centrioles and interacts with oral-facial-digital syndrome 1 (ODF1), which is associated with nephronophthisis-related ciliopathies (NPHP-RC), a recessive disorder that is characterized by dysplasia or degeneration of the kidney, retina and cerebellum. SDCCAG8 exists as four alternatively spliced isoforms and is encoded by a gene located on humanc chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SDCCAG8 polyclonal antibody detects endogenous levels of SDCCAG8 protein.

Bioworld Molecular Weight: ~ 41 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of SDCCAG8 polyclonal antibody at 1:500 dilution Lane 1: HEK293T whole cell lysate
Lane 2: RAW264.7 whole cell lysate Lane 3: H9C2 whole cell lysate

Immunogen: A synthetic peptide corresponding to residues in Human SDCCAG8.

Conjugate: Unconjugated

Modification: Unmodified