Product Description

SEMA3A (P737) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS3691-50, BS3691-100

Sizes: 50µl, 100µl

Swiss-Prot: Q14563

Host: Rabbit

Reactivity: Human, Rat

Applications: WB, IHC

Background: Semaphorin 3A (Sema3A) may play a particularly interesting role in limiting axon regeneration since it is expressed in meningeal fibroblasts that invade the injured spinal cord and surround the glial scar. In addition, the Sema3A co receptors, Neuropilin 1 and Plexin A1, are expressed on axons that regenerate up to the injured region, but do not cross this Sema3A containing region. Thus, Sema3A and its co receptors may have important roles in regulating axon guidance during neuronal development and after neuronal injury.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: SEMA3A (P737) polyclonal antibody detects endogenous levels of SEMA3A protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of SEMA3A (P737) pAb at 1:1000 dilution
Lane 1: HEK293T whole cell lysate (40ug)
Lane 2: A549 whole cell lysate (40ug)
Lane 3: PC3 whole cell lysate (40ug)
Lane 4: C6 whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of SEMA3A (P737) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

Bioworld Molecular Weight: ~ 89 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Semaphorin-3A; Semaphorin III; Sema III; SEMAD; SEMA3A

Immunogen: Synthetic peptide, corresponding to amino acids 702-756 of Human SEMA3A.

Conjugate: Unconjugated

Modification: Unmodified