SEMA3E Polyclonal Antibody
Catalogue Numbers: BS60460-50, BS60460-100
Sizes: 50µl, 100µl
Alternative Name: Semaphorin-3E; Semaphorin 3E; KIAA0331; SEMAH
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: O15041
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: Semaphorins are a family of cell surface and secreted proteins involved in neural development that are conserved from insects to humans. Members of this family are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular “semaphorin” domain of approximately 500 amino acids containing 14-16 cysteines, blocks of conserved sequences and no obvious repeats. SEMA3E is a secreted semaphorin with 775 amino acids. Mutations in the SEMA3E gene are associated with CHARGE syndrome, a disorder characterized by cranial nerve dysfunction, coloboma of the eye, choanal atresia, inner and external ear abnormalities, cardiac anomalies, genitourinary abnormalities, and growth retardation.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: SEMA3E polyclonal antibody detects endogenous levels of SEMA3E protein.
Bioworld Molecular Weight: ~ 89 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of SEMA3E polyclonal antibody at 1:500 dilution
Lane 1: A549 cell lysate
Lane 2: Mouse liver tissue lysate
Lane 3: Rat liver tissue lysate
Immunogen: A synthetic peptide corresponding to residues in Human SEMA3E.
Conjugate: Unconjugated
Modification: Unmodified