Semaphorin 3A Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A12967-20, A12967-100
Citations, Manuals and MSDS Available upon request.
Background: This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Mouse, Rat
Protein Weight: 89kDa
Observed Molecular Weight: 89kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 10371
SWISS: Q14563
Alternate Names: HH16; SemD; COLL1; SEMA1; SEMAD; SEMAL; coll-1; Hsema-I; SEMAIII; Hsema-III; Semaphorin 3A
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cell Biology Developmental Biology, Cytoskeleton, Actins, Neuroscience, Cardiovascular, Heart, Cardiogenesis, Cardiac arrhythmias, Hypertrophy.
NCBI Alias: SEMA3A
Research Use Only