Product Description

Semaphorin 4D Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS46194-50, BS46194-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regμlates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granμle cells and of endothelial cells. Plays a role in the immune system, induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IHC, ICC/IF

Alternate Names: CD100, COLL4, SEMAJ, coll-4, C9orf164, M-sema-G

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide of human Semaphorin 4D

Dilution: WB: 1:1000-1:5000 IHC: 1:20-1:100 ICC/IF: 1:20-1:100

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 120 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q92854

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only