SENP5 rabbit pAb - ES3420

SENP5 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3420-50, ES3420-100

Citations, Manuals and MSDS Available upon request.

Background: The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009],

Alternate Name: SENP5; FKSG45; Sentrin-specific protease 5; Sentrin/SUMO-specific protease SENP5

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Monkey

Immunogen: The antiserum was produced against synthesized peptide derived from human SENP5. AA range:651-700

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 86kD

Human Gene ID: 205564

Human SWISS Prot NO: Q96HI0

Subcellular Location: Nucleus, nucleolus.

Research Use Only