Septin 3 Polyclonal Antibody-BS62412

Septin 3 Polyclonal Antibody

Catalogue Numbers: BS62412-50, BS62412-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Swiss-Prot: Q9UH03

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: WB

All Applications: WB:1:500~1:1000

Background: The septins are a family of GTPase enzymes, some of which are required for cytokinesis and others of which are associated with exocytosis. Members of the Septin family can form heteropolymer complexes and also play a role in the organization of new growth in organisms. The transcriptional regulation of all septins is complex, resulting in alternatively spliced variants. Septin 10, a 517 residue polypeptide which localizes to the cytoplasm and nucleus, shares closest homology to Septin 6 and Septin 8. Septin 10 is expressed ubiquitously, though most abundantly in the placenta, lung, kidney, heart, skeletal muscles, liver and various tumor cell lines. Like other Septin family members, Septin 10 displays GTP-binding and GTPase activity. Additionally, Septin 10 is potentially involved in cytokinesis. Upon maturation induced by lipopolysaccharide (LPS), dendritic cells express upregulated amounts of Septin 10.

Purification and Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Septin 3 polyclonal antibody detects endogenous levels of Septin 3 protein.

Extra Notes: Western blot (WB) analysis of Septin 3 polyclonal antibody at 1:500 dilution
LaneA:The brain tissue lysate of Mouse
LaneB:The brain tissue lysate of Rat
LaneC:Hela whole cell lysate
LaneD:The kidney tissue lysate of Mouse
LaneE:The kidney tissue lysate of Rat

Bioworld Molecular Weight: ~ 45 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Neuronal-specific septin-3; SEPTIN3; SEP3; SEPT3

Immunogen: Synthetic peptide, corresponding to Human Septin 3.

Conjugate: Unconjugated

Modification: Unmodified