Product Description

Septin 7 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11581-50, MB11581-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q16181

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ICC/IF

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200

Background: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (PubMed:25588830).

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 51 kDa; Observed MW: 51 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of SEPT7 in 3T3, rat brain lysates using Septin 7 antibody., Western blot analysis of SEPT7 in Hela, MCF-7, mouse brain lysates using SEPT7 antibody.

Alternative Name: septin 7; CDC3; CDC10; SEPT7; SEPT7A; NBLA02942

Immunogen: Recombinant protein of human SEPT7

Conjugate: Unconjugated

Modification: Unmodified