SERCA1/ATP2A1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A10104-20, A10104-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes one of the SERCA Ca (2+) -ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Mouse
Protein Weight: 110kDa
Observed Molecular Weight: 110kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 487
SWISS: O14983
Alternate Names: ATP2A; SERCA1; SERCA1/ATP2A1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:200 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Neuroscience, Calcium Signaling, Neurodegenerative Diseases, Cardiovascular, Heart, Cardiovascular diseases, Heart disease.
NCBI Alias: ATP2A1
Research Use Only