SERCA1 rabbit pAb - ES3428

SERCA1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3428-50, ES3428-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes one of the SERCA Ca (2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms. [provided by RefSeq, Oct 2013],

Alternate Name: ATP2A1; Sarcoplasmic/endoplasmic reticulum calcium ATPase 1; SERCA1; SR Ca (2+)-ATPase 1; Calcium pump 1; Calcium-transporting ATPase sarcoplasmic reticulum type; fast twitch skeletal muscle isoform; Endoplasmic reticulum class 1/2 Ca (2+) AT

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat; Salamander; Pig

Immunogen: The antiserum was produced against synthesized peptide derived from human ATP2A1. AA range:548-597

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 100kD

Human Gene ID: 487

Human SWISS Prot NO: O14983

Subcellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein.

Research Use Only