Product Description

Serine/threonine-protein kinase BGLF4 Polyclona Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA29746-50, RA29746-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: P13288 BGLF4 protein (BGLF4) Human herpesvirus 4 catalytic activity:ATP + a protein = ADP + a phosphoprotein., function:Plays many key roles by phosphorylating several proteins including the viral DNA processivity factor BMRF1, EBNA1 or EBNA2. Required for efficient lytic DNA replication and release of nucleocapsids from the nucleus. Contributes to the compaction of host cell chromatin in cells undergoing lytic replication, presumably by phosphorylating the host condensin complex and host TOP2A. Induces disassembly of the nuclear lamina by phosphorylating with host LMNA. Phosphorylates substrates involved in capsid assembly and DNA packaging. Facilitates the switch from latent to lytic DNA replication by down-regulating EBNA1 replication function. Phosphorylates the viral immediate-early protein BZLF1., similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family., similarity:Contains 1 protein kinase domain., subcellular location:the protein is present at discrete sites in nuclei, called replication compartments where viral DNA replication occurs.,

Reactivity: Human virus

Host: Rabbit

Applications: ELISA

Clonality: Polyclonal

Dilution: ELISA (peptide) 1:5000-20000

Storage: -20°C/1 year

Human SwissProt Number: P13288

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only