Serine/threonine-protein kinase BGLF4 Polyclona Antibody - RA29746

Serine/threonine-protein kinase BGLF4 Polyclona Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA29746-50, RA29746-100

Citations, Manuals and MSDS Available upon request.

Background: P13288 BGLF4 protein (BGLF4) Human herpesvirus 4 catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Plays many key roles by phosphorylating several proteins including the viral DNA processivity factor BMRF1, EBNA1 or EBNA2. Required for efficient lytic DNA replication and release of nucleocapsids from the nucleus. Contributes to the compaction of host cell chromatin in cells undergoing lytic replication, presumably by phosphorylating the host condensin complex and host TOP2A. Induces disassembly of the nuclear lamina by phosphorylating with host LMNA. Phosphorylates substrates involved in capsid assembly and DNA packaging. Facilitates the switch from latent to lytic DNA replication by down-regulating EBNA1 replication function. Phosphorylates the viral immediate-early protein BZLF1.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subcellular location:the protein is present at discrete sites in nuclei, called replication compartments where viral DNA replication occurs.,

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: ELISA (peptide) 1:5000-20000

Applications: ELISA

Species Cross-Reactivity: Human virus

SWISS: P13288

Source: Rabbit

Research Use Only