SETMAR rabbit pAb - ES7157

SETMAR rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7157-50, ES7157-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013],

Alternate Name: SETMAR; Histone-lysine N-methyltransferase SETMAR; SET domain and mariner transposase fusion gene-containing protein; HsMar1; Metnase

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human SETMAR. AA range:350-400

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 6419

Human SWISS Prot NO: Q53H47

Subcellular Location: Nucleus. Chromosome. Recruited on damaged DNA at sites of double-strand breaks.

Research Use Only