SF3B1 (phospho-Thr313) Rabbit Polyclonal Antibody - RA29757

SF3B1 (phospho-Thr313) Rabbit Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA29757-50, RA29757-100 Citations, Manuals and MSDS Available upon request. Background: splicing factor 3b subunit 1 (SF3B1) Homo sapiens This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP) . The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008], Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: WB 1:1000-2000 Alternative Names: Splicing factor 3B subunit 1 (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155) Applications: WB Species Cross-Reactivity: Human; Mouse GeneID (Human): 23451 Protein MW (KDa): 145 SWISS: O75533 Source: Rabbit Research Use Only