SF3B3 Monoclonal Antibody-MB11586

SF3B3 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11586-50, MB11586-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q15393

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ICC/IF

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200

Background: Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 136 kDa; Observed MW: 136 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of SF3B3 in Raw264.7 lysates using SF3B3 antibody., Western blot analysis of SF3B3 in SH-SY5Y, C6 lysates using SF3B3 antibody., Immunocytochemistry analysis of SF3B3 in Hela using SF3B3 antibody, and DAPI

Alternative Name: SF3B3; KIAA0017; SAP130; Splicing factor 3B subunit 3; Pre-mRNA-splicing factor SF3b 130 kDa subunit; SF3b130; STAF130; Spliceosome-associated protein 130; SAP 130

Immunogen: A synthetic peptide of human SF3B3

Conjugate: Unconjugated

Modification: Unmodified