Product Description

SFPQ Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11587-50, MB11587-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P23246

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-F, IHC-P, ICC/IF

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Background: DNA- and RNA binding protein, involved in several nuclear processes. Essential pre-mRNA splicing factor required early in spliceosome formation and for splicing catalytic step II, probably as an heteromer with NONO. Binds to pre-mRNA in spliceosome C complex, and specifically binds to intronic polypyrimidine tracts.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 76 kDa; Observed MW: 100 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunocytochemistry analysis of SFPQ in 293T using SFPQ antibody, and DAPI., Western blot analysis of SFPQ in K562, rat Brain, C6, 3T3, Hela lysates using SFPQ antibody., Immunohistochemistry analysis of paraffin-embedded Human lung cancer tissue using SFPQ antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: PSF; POMP100; PPP1R140

Immunogen: A synthetic peptide of human SFPQ

Conjugate: Unconjugated

Modification: Unmodified