Product Description

SFRS8 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS5952-50, BS5952-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: SWAP (suppressor of white apricot protein homolog), also known as SFRS8 (splicing factor, arginine/serine-rich 8), is the 951 amino acid human homolog of a Drosophilia splicing protein. Localized to the nucleus, SWAP contains two SURP repeats through which it is thought to mediate splicing events, possibly regμlating the alternative splicing of Fibronectin and CD45RC. SWAP regμlates its own expression levels (via control of splicing in its first two introns) and may act in tandem with other arginine/serine-rich splicing factors to control protein expression. The gene encoding SWAP is located on a region of chromosome 12 that is related to asthma susceptibility, possibly indicating a role for SWAP in the development of asthma. Mμltiple isoforms of SWAP exist due to alternative splicing events.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Splicing factor, suppressor of white-apricot homolog, Splicing factor, arginine/serine-rich 8, Suppressor of white apricot protein homolog, SFSWAP, SFRS8, SWAP

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 251-296 of Human SFRS8.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: SFRS8 polyclonal antibody detects endogenous levels of SFRS8 protein.

Molecular Weight: ~ 105 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q12872

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only