SFT2D3 Polyclonal Antibody
Catalogue Numbers: BS61480-50, BS61480-100
Sizes: 50µl, 100µl
Alternative Name: Vesicle transport protein SFT2C; SFT2 domain-containing protein 3; SFT2D3
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q587I9
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: SFT2D3 (SFT2 domain-containing protein 3) is a 215 amino acid multi-pass membrane protein that belongs to the SFT2 family. SFT2D3 may be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. The SFT2D3 gene is conserved in chimpanzee, cow, mouse, rat, zebrafish, fruit fly, mosquito and C.elegans, and maps to human chromosome 2q14.3. As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alström syndrome, is related to mutations in the ALMS1 gene. Chromosome 2 contains a probable vestigial second centromere as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: SFT2D3 polyclonal antibody detects endogenous levels of SFT2D3 protein.
Bioworld Molecular Weight: ~ 21 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of SFT2D3 polyclonal antibody at 1:500 dilution
Lane 1: PC12 whole cell lysate(40ug)
Lane 2: Jurkat whole cell lysat(40ug)
Lane 3: NIH-3T3 whole cell lysate(40ug)
Immunogen: Synthetic peptide, corresponding to amino acids 101-146 of Human SFT2D3.
Conjugate: Unconjugated
Modification: Unmodified