SG196 rabbit pAb - ES13139

SG196 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES13139-50, ES13139-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a protein that may be involved in the presentation of the laminin-binding O-linked carbohydrate chain of alpha-dystroglycan (a-DG), which forms transmembrane linkages between the extracellular matrix and the exoskeleton. Some pathogens use this O-linked carbohydrate unit for host entry. Loss of function compound heterozygous mutations in this gene were found in a human patient affected by the Walker-Warburg syndrome (WWS) phenotype. Mice lacking this gene contain misplaced neurons (heterotopia) in some regions of the brain, possibly from defects in neuronal migration. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013],

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human SG196 AA range: 178-228

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 84197

Human SWISS Prot NO: Q9H5K3

Subcellular Location: Endoplasmic reticulum membrane; Single-pass type II membrane protein.

Research Use Only