Product Description

SH3GLB2 Polyclonal Antibody

Catalogue Numbers: BS62482-50, BS62482-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9NR46

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB:1:500~1:1000 IHC:1:50~1:200

Background: The Endophilins comprise a family of proteins that associate with Amphiphysin, Synaptojanin and Dynamin and are implicated in presynaptic vesicle trafficking at nerve terminals. The expression patterns of the Endophilins are consistent with their cellular functions at the neuronal synapse. Endophilin B1 is a member of the B subgroup of the Endophilin family that is required for maintenance of mitochondrial morphology and for the regulation of the outer mitochondrial membrane dynamics. Endophilin B2 is also a member of the Endophilin B subroup that is ubiquitously expressed but shows highest levels in brain, adult lung, ovary, and spinal cord. Decreased levels of Endophilin B2 are found in Down Syndrome and may reflect brain dysgenesis.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SH3GLB2 polyclonal antibody detects endogenous levels of SH3GLB2 protein.

Extra Notes: Western blot (WB) analysis of SH3GLB2 polyclonal antibody at 1:500 dilution
LaneA:BV2 whole cell lysate
LaneB:PC12 whole cell lysate

Bioworld Molecular Weight: ~ 44 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Endophilin-B2; SH3 domain-containing GRB2-like protein B2; SH3GLB2; KIAA1848; PP578

Immunogen: Synthetic peptide, corresponding to Human SH3GLB2.

Conjugate: Unconjugated

Modification: Unmodified