Product Description

SHMT1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS77029-50, BS77029-100

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P34896

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IF/ICC

All Applications: WB,1:500 - 1:2000 | IF/ICC,1:50 - 1:100

Background: This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Unmodification

Extra Notes: Immunofluorescence analysis of U-2 OS cells using SHMT1 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: SHMT1; CSHMT; SHMT

Immunogen: Recombinant fusion protein of human SHMT1(NP_683718.1).

Conjugate: Unconjugated

Modification: Unmodified