Sicilian Phlebo Virus Nucleocapsid Protein Polyclonal Antibody - NCP0136P

Sicilian Phlebo Virus Nucleocapsid Protein Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: NCP0136P-50, NCP0136P-100

Swiss-Prot: EF201822.1

Host: Rabbit

Reactivity: SFSV

Applications: WB, ELISA

All Applications: WB: 1:500~1:2000
ELISA: 1:5000~10000

Background: Sandfly fever Sicilian virus (SFSV) is one of the most widespread and frequently identified members of the genus Phlebovirus (order Bunyavirales, family Phenuiviridae) infecting humans. Being transmitted by Phlebotomus sandflies, SFSV causes a self-limiting, acute, often incapacitating febrile disease ("sandfly fever," "Pappataci fever," or "dog disease") that has been known since at least the beginning of the 20th century. Similarly to other pathogenic phleboviruses, SFSV suppresses the induction of the antiviral type I interferon (IFN) system in an NSs-dependent manner. SFSV NSs interfered with the TBK1-interferon regulatory factor 3 (IRF3) branch of the RIG-I signaling pathway but not with NF-κB activation.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Sicilian phlebovirus Nucleocapsid Protein polyclonal antibody detects endogenous levels of SFSV protein.

Note: For research use only, not for use in diagnostic procedure.

Immunogen: Recombinant protein of SFSV.

Conjugate: Unconjugated

Modification: Unmodified