SIDT2 Polyclonal Antibody-BS77217

SIDT2 Polyclonal Antibody

Catalogue Numbers:BS77217-50, BS77217-100

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q8NBJ9

Host: Rabbit

Reactivity: Rat

Applications: IF/ICC

All Applications: IF/ICC,1:50 - 1:100

Background: Mediates the translocation of RNA and DNA across the lysosomal membrane during RNA and DNA autophagy (RDA, a process in which RNA or DNA is directly imported into lysosomes in an ATP-dependent manner, and degraded. Involved in the uptake of single-stranded oligonucleotides by living cells, a process called gymnosis. In vitro, mediates the uptake of linear DNA more efficiently than that of circular DNA, but exhibits similar uptake efficacy toward RNA and DNA. Binds long double-stranded RNA (dsRNA (500 - 700 base pairs, but not dsRNA shorter than 100 bp (By similarity.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Unmodification

Note: For research use only, not for use in diagnostic procedure.
Alternative Name: SIDT2;CGI-40

Immunogen: Recombinant fusion protein of human SIDT2(NP_001035545.1).

Conjugate: Unconjugated

Modification: Unmodified