SIM1 Rabbit Polyclonal Antibody - BT-AP04750

SIM1 Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP04750-20, BT-AP04750-50, BT-AP04750-100

Citations, Manuals and MSDS Available upon request.

Background: SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested. Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis|it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull characteristics)| abnormalities of brain development| and/or mental retardation of Down syndrome.

Research Areas: Neuroscience

Target Protein: SIM1

Applications: WB

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: SIM1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P81133; Mouse: Q61045

Synonyms: SIM1; Single-minded homolog 1; Class E basic helix-loop-helix protein 14; bHLHe14

GeneID: Human: 6492; Mouse: 20464

Research Use Only