SIN3B Polyclonal Antibody-BS5930

SIN3B Polyclonal Antibody

Catalogue Numbers: BS5930-50, BS5930-100

Sizes: 50µl, 100µl

Alternative Name: Paired amphipathic helix protein Sin3b; Histone deacetylase complex subunit Sin3b; Transcriptional corepressor Sin3b; KIAA0700

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O75182

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IF

All Applications: WB: 1:500~1:1000
IF: 1:50~1:200

Background: Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SIN3B polyclonal antibody detects endogenous levels of SIN3B protein.

Bioworld Molecular Weight: ~ 40, 129, 133 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of SIN3B polyclonal antibody at 1:500 dilution
Lane 1: Hela cell lysate
Lane 2: sp2/0 cell lysate

Immunogen: Synthetic peptide, corresponding to amino acids 260-305 of Human SIN3B.

Conjugate: Unconjugated

Modification: Unmodified