Product Description

Sin3B Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA29833-50, RA29833-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: function:Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription., similarity:Contains 3 PAH (paired amphipathic helix) repeats., subunit:Interacts with FOXK1/MNF, MXI, MAD, NCOR1 and SAP30. Interaction with SDS3 enhances the interaction with HDAC1 to form a complex. Interacts with MAD3, MAD4, MAEL, REST and SETDB1 (By similarity). Interacts with HCFC1.,

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, IF/ICC, ELISA

Alternate Names: SIN3B, KIAA0700, Paired amphipathic helix protein Sin3b, Histone deacetylase complex subunit Sin3b, Transcriptional corepressor Sin3b

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight: 130

Protein Molecular Weight (kDa): 130

Storage: -20°C/1 year

Human Gene ID: 23309

Human SwissProt Number: O75182

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only