SIPA1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A12253-20, A12253-100
Citations, Manuals and MSDS Available upon request.
Background: The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 112kDa
Observed Molecular Weight: 130kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 6494
SWISS: Q96FS4
Alternate Names: SPA1; SIPA1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Signal Transduction, G protein signaling, Small G proteins, Cell Biology Developmental Biology, Apoptosis, Cell Cycle, Cell cycle inhibitors, Stem Cells, Embryonic Stem Cells.
NCBI Alias: SIPA1
Research Use Only