SIPA1 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A12253-20, A12253-100
Citations, Manuals and SDS Available upon request.
Background: The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.
Synonyms: SPA1; SIPA1
GeneID: 6494
Swiss Prot: Q96FS4
Tested Applications: ELISA, WB
Reactivity: Human, Mouse
Calculated Molecular Weight: 112kDa
Observed Molecular Weight: 130kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 763-1042 of human SIPA1 (NP_694985.29).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000
Research Areas: Epigenetics Nuclear Signaling, Signal Transduction, G protein signaling, Small G proteins, Cell Biology Developmental Biology, Apoptosis, Cell Cycle, Cell cycle inhibitors, Stem Cells, Embryonic Stem Cells
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: Raji, K-562, HeLa, LO2, Mouse spleen
Cellular Location: Cytoplasm, EndoMembrane System, Nucleus, Peripheral Membrane Protein, Perinuclear Region,
Keywords: 6494, sc-23028, sc-23030, sc-67095, sc-67094, SIPA1, SPA1, signal-induced proliferation-associated 1, signal-induced proliferation-associated protein 1, GTPase-activating protein Spa-1, p130 SPA-1, signal-induced proliferation-associated gene 1, sipa-1, Q96FS4, Signal-Induced Proliferation-Associated 1, GTPase-Activating Protein Spa-1, P130 SPA-1, Sipa-1, Signal-Induced Proliferation-Associated Protein 1, Signal-Induced Proliferation-Associated Gene 1, sc23028, sc 23028, sc23030, sc 23030, sc67095, sc 67095, sc67094, sc 67094, Sipa 1, p130 SPA 1
Symbol: SIPA1
Category: Polyclonal Antibodies
Research Use Only