Product Description

SIRT1 (2G10) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3056-50, MB3056-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: Q96EB6

Host: Mouse

Reactivity: Human

Applications: WB, IP,

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG2b

Bioworld Molecular Weight: Calculated MW: 82 kDa; Observed MW: 120 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of SIRT1 in Hela, Jurkat, Ramos, A549 and CEM lysates using SIRT1 antibody., Immunoprecipitation analysis of SIRT1 in Hela lysates using SIRT1 antibody.

Alternative Name: SIRT1; SIR2L1; NAD-dependent protein deacetylase sirtuin-1; hSIRT1; Regulatory protein SIR2 homolog 1; SIR2-like protein 1; hSIR2

Immunogen: Purified recombinant human SIRT1 protein fragments expressed in E.coli.

Conjugate: Unconjugated

Modification: Unmodified