Product Description

SIRT1 (phospho-Ser549) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA29841-50, RA29841-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: sirtuin 1 (SIRT1) Homo sapiens This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Alternate Names: NAD-dependent protein deacetylase sirtuin-1 (hSIRT1;EC 3.5.1.-;Regulatory protein SIR2 homolog 1;SIR2-like protein 1;hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)]

Clonality: Polyclonal

Dilution: WB 1:1000-2000 ELISA 1:5000-20000

Molecular Weight: 78

Protein Molecular Weight (kDa): 78

Storage: -20°C/1 year

Human Gene ID: 23411

Human SwissProt Number: Q96EB6

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only