SIRT2 (1D4) Monoclonal Antibody-MB3013

SIRT2 (1D4) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3013-50, MB3013-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: Q8IXJ6

Host: Mouse

Reactivity: Human, Mouse, Rat

Applications: WB, ICC/IF

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200

Background: Participate in a variety of cellular functions, including histone deacetylation, gene silencing, chromosomal stability, and aging. SIRT2, a human homolog of the yeast SIR2, functions as transcriptional silencing mediator at mating-type loci, telomeres and ribosomal gene clusters. SIRT2 expression increases dramatically during mitosis and is multiply phosphorylated at the G(2)/M transition of the cell cycle.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG2b

Bioworld Molecular Weight: Calculated MW: 43 kDa; Observed MW: 43 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of SirT2 in PC-12, rat Brain and mouse Brain lysates using SirT2 antibody., Immunofluorescence analysis of SIRT2 in Hela using SirT2 antibody and Histone H3.1 antibody., Western blot analysis of SIRT2 in rat Cerebral Cortex and rat Brain lysates using SirT2 antibody.

Alternative Name: SIRT2; SIR2L; SIR2L2; NAD-dependent protein deacetylase sirtuin-2; Regulatory protein SIR2 homolog 2; SIR2-like protein 2

Immunogen: Purified recombinant human SirT2 protein expressed in E.coli.

Conjugate: Unconjugated

Modification: Unmodified