SIRT3 Monoclonal Antibody-MB11599

SIRT3 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11599-50, MB11599-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q9NTG7

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-P

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100

Background: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 44 kDa; Observed MW: 28 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of SIRT3 in Jurkat, Hela lysates using SIRT3 antibody., Immunohistochemistry analysis of paraffin-embedded Human breast cancer using SIRT3 antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.

Alternative Name: SIR2L3

Immunogen: A synthetic peptide of human SIRT3

Conjugate: Unconjugated

Modification: Unmodified