SIRT6 (6C9) Monoclonal Antibody-MB3015

SIRT6 (6C9) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3015-50, MB3015-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: Q8N6T7

Host: Mouse

Reactivity: Human, Mouse, Rat, Monkey

Applications: WB, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background: The Silent Information Regulator (Sir2) family of genes is a highly conserved group of genes that encode nicotinamide adenine dinucleotide (NAD)-dependent protein deacetylases, also known as class III histone deacetylases. SirT6, a mammalian homolog of Sir2, is a nuclear, chromatin-associated protein that promotes the normal maintenance of genome integrity mediated by the base excision repair (BER) pathway.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG1

Bioworld Molecular Weight: Calculated MW: 39 kDa; Observed MW: 42 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of SIRT6 in Jurkat, MCF-7, HCT116, K562, COS7, C2C12, 3T3 and Hela lysates using SIRT6 antibody., Immunofluorescence analysis of SIRT6 in Hela using SIRT6 antibody., Immunoprecipitation analysis of SIRT6 in Hela lysates using SIRT6 antibody.

Alternative Name: 2810449N18Rik; AI043036; Mono ADP ribosyltransferase sirtuin 6; NAD-dependent protein deacetylase sirtuin-6; Regulatory protein SIR2 homolog 6; Regulatory protein SIR2 homolog; SIR2 like 6; SIR2 like protein 6; Sir2 related protein type 6; SIR2-like protein 6; SIR2

Immunogen: Purified recombinant human SIRT6 protein expressed in E.coli.

Conjugate: Unconjugated

Modification: Unmodified