Product Description

SKI-1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA29848-50, RA29848-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: membrane bound transcription factor peptidase, site 1 (MBTPS1) Homo sapiens This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction. [provided by RefSeq, Feb 2014],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Alternate Names: MBTPS1, KIAA0091, S1P, SKI1, Membrane-bound transcription factor site-1 protease, Endopeptidase S1P, Subtilisin/kexin-isozyme 1, SKI-1

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight: 130

Protein Molecular Weight (kDa): 130

Storage: -20°C/1 year

Human Gene ID: 8720

Human SwissProt Number: Q14703

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only