Product Description

SKOR2 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65800-50, BS65800-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The sloan kettering virus (Ski) family of nuclear oncoproteins act as transcriptional regμlators of TGF-尾 by interacting directly with SMAD proteins. Fussel-18 (functional Smad-suppressing element on chromosome 18), also known as SKOR2 (Ski family transcriptional corepressor 2), LBX1 corepressor 1-like protein, ladybird homeobox corepressor 1-like protein or CORL2, is a 1, 001 amino acid protein that belongs to the Ski family. Localizing to nucleus as well as cytoplasm, Fussel-18 is expressed in cerebellum, spinal cord and testis. Fussel-18 acts as an antagonist to TGF-尾 in the nervous system, possibly by functioning as a transcriptional repressor of SMAD2 and SMAD3. Existing as two alternatively spliced isoforms, the gene encoding Fussel-18 maps to human chromosome 18q21.1 and mouse chromosome 18 E3.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Dog, Cow, Sheep

Host: Rabbit

Applications: IHC-P

Alternate Names: CORL2, Functional smad suppressing element 18, Functional Smad-suppressing element on chromosome 18, Fussel-18, FUSSEL18, Ladybird homeobox corepressor 1-like protein, LBX1 corepressor 1-like protein, SKI family transcriptional corepressor 2, SKOR2, SKOR2_HUMAN

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human SKOR2:871-970/100

Dilution: IHC-P=1:100-500

Purification: affinity purified by Protein A

Specificity: SKOR2 Polyclonal Antibody detects endogenous levels of SKOR2 protein.

Molecular Weight: ~104 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -27°C long term. Avoid freeze-thaw cycles.

SwissProt: Q2VWA4

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only