SKP1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A2566-20, A2566-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein (s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 19kDa
Observed Molecular Weight: 19kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 6500
SWISS: P63208
Alternate Names: OCP2; p19A; EMC19; SKP1A; OCP-II; TCEB1L; SKP1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Kinase, Cell Biology Developmental Biology, Cell Cycle, Centrosome, Ubiquitin, Ubiquitin-Proteasome Signaling Pathway.
NCBI Alias: SKP1
Research Use Only