SLAF7 rabbit pAb - ES10867

SLAF7 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES10867-50, ES10867-100

Citations, Manuals and MSDS Available upon request.

Background: function:Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion. Isoform 3 does not mediate any activation. SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro)., similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain., tissue specificity:Expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. The isoform 3 is expressed at much lower level tha isoform 1.,

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from part region of human protein AA range: 41-90

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 36kD

Human Gene ID: 57823

Human SWISS Prot NO: Q9NQ25

Subcellular Location: Membrane; Single-pass type I membrane protein.

Research Use Only