Product Description

SLC16A13 (L423) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS3143-50, BS3143-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Monocarboxylates, such as lactate and pyruvate, play an integral role in cellμlar metabolism. Lactic acid is produced in large quantities as a resμlt of glycolysis, which provides the majority of ATP to cells under normal physiological conditions. However, accumμlation of lactic acid leads to a decrease in intracellμlar pH and, thus, to a cessation of glycolysis. In order for glycolysis to continue at a high rate, lactic acid must be transported out of the cell. This transport process is carried out by a family of monocarboxylate transporters (MCTs), which function as proton symports and are stereoselective for L-lactate. MCT13 (Monocarboxylate transporter 13), also known as SLC16A13 (Solute carrier family 16 member 13), is a 426 amino acid mμlti-pass membrane protein that belongs to the MCT transport family. Functioning as a proton-linked monocarboxylate transporter, MCT13 catalyzes the rapid transports of molecμles, such as lactate, across the plasma membrane.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Monocarboxylate transporter 13, MCT 13, Solute carrier family 16 member 13, SLC16A13, MCT13

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 389-442 of Human SLC16A13.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: SLC16A13 (L423) polyclonal antibody detects endogenous levels of SLC16A13 protein.

Molecular Weight: ~ 40 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q7RTY0

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only