Product Description

SLC16A13 (L423) Polyclonal Antibody

Catalogue Numbers: BS3143-50, BS3143-100

Sizes: 50µl, 100µl

Alternative Name: Monocarboxylate transporter 13; MCT 13; Solute carrier family 16 member 13; SLC16A13; MCT13

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q7RTY0

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Monocarboxylates, such as lactate and pyruvate, play an integral role in cellular metabolism. Lactic acid is produced in large quantities as a result of glycolysis, which provides the majority of ATP to cells under normal physiological conditions. However, accumulation of lactic acid leads to a decrease in intracellular pH and, thus, to a cessation of glycolysis. In order for glycolysis to continue at a high rate, lactic acid must be transported out of the cell. This transport process is carried out by a family of monocarboxylate transporters (MCTs), which function as proton symports and are stereoselective for L-lactate. MCT13 (Monocarboxylate transporter 13), also known as SLC16A13 (Solute carrier family 16 member 13), is a 426 amino acid multi-pass membrane protein that belongs to the MCT transport family. Functioning as a proton-linked monocarboxylate transporter, MCT13 catalyzes the rapid transports of molecules, such as lactate, across the plasma membrane.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SLC16A13 (L423) polyclonal antibody detects endogenous levels of SLC16A13 protein.

Bioworld Molecular Weight: ~ 40 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of SLC16A13 (L423) pAb at 1:500 dilution
Lane 1: C6 whole cell lysate(40ug)
Lane 2: 3T3-L1 whole cell lysate(40ug)
Lane 3: MCF-7 whole cell lysate(40ug)
Lane 4: HepG2 whole cell lysate(40ug)
Lane 5: H1792 whole cell lysate(20ug)

Immunogen: Synthetic peptide, corresponding to amino acids 389-442 of Human SLC16A13.

Conjugate: Unconjugated

Modification: Unmodified