Product Description

SLC1A4 Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Sizes: 50µl, 100µl

Catalogue Numbers: BS7488-50, BS7488-100

Swiss-Prot: P43007

Host: Rabbit

SLC1A4 Polyclonal Antibody-BS7488

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB: 1:500~1:2000
IHC: 1:50~1:200

Background: SLC1A4, also known as ASCT1, is a neutral amino acid transporter. Its other name, ASCT1, was given because it mediates obligatory exchange of alanine, serine, cysteine, and threonine (1). SLC1A4 mediates the efflux of glutamate from the neuron into the synaptic junction via calcium-independent release, as well as mediating the efflux of L-serine from glial cells and its uptake by neurons (2). SLC1A4-mediated transport is shown to involve a symmetrical potassium-independent electroneutral exchange of neutral amino acids and sodium, such that the current activated during transport is carried only by chloride ions (3).

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: SLC1A4 polyclonal antibody detects endogenous levels of SLC1A4 protein.

Bioworld Molecular Weight: ~56 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of SLC1A4 polyclonal antibody, Immunohistochemistry (IHC) analysis of SLC1A4 polyclonal antibody

Alternative Name: Alanine/serine/cysteine/threonine transporter 1;
ASCT-1;
ASCT1;
AW045657;
Glutamate/neutral amino acid transporter;
Neutral amino acid transporter A;
OTTHUMP00000159933;
OTTHUMP00000235138;
SATT;
SATT_HUMAN;
SLC1A4;
Solute carrier family 1 (glutamate/neutral amino acid transporter), member 4;
Solute carrier family 1 member 4;

Immunogen: Recombinant full length Human SLC1A4.

Modification: Unmodified

Conjugate: Unconjugated