SLC25A6 (R155) Polyclonal Antibody-BS3799

SLC25A6 (R155) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS3799-50, BS3799-100

Sizes: 50µl, 100µl

Swiss-Prot: P12236

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

Background: ANT2 (adenine nucleotide translocator 2), also known as SLC25A5 (solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5), T2, T3, 2F1 or AAC2, is a 298 amino acid multi-pass membrane protein that localizes to the inner mitochondrial membrane and contains three solcar repeats. Existing as one of the most abundant mitochondrial proteins, ANT2 functions as a homodimer that facilitates the exchange of ADP and ATP between the mitochondrion and the cytosol, thus linking the compartment of ATP production (within the mitochondrion) to the areas of ATP utilization (within the cytosol). Suppression of ANT2 in breast cancer cells results in apoptosis and tumor growth inhibition, suggesting that ANT2 may be involved in carcinogenesis. ANT3 (adenine nucleotide translocator 2) is a 298 amino acid mitochondrial protein that functions in a similar manner to ANT2 but, unlike ANT2, may also play a role in the formation of the permeability transition pore complex (PTPC), a structure that is important for the regulation of apoptosis.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: SLC25A6 (R155) polyclonal antibody detects endogenous levels of SLC25A6 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of SLC25A6 (R155) pAb at 1:1000 dilution
Lane 1: H1792 whole cell lysate (40ug)
Lane 2: HepG2 whole cell lysate (40ug)
Lane 3: The Testis tissue lysate of Mouse (40ug)
Lane 4: The Testis tissue lysate of Rat (40ug)
Lane 5: HEK293T whole cell lysate (20ug), Immunohistochemistry (IHC) analyzes of SLC25A6 (R155) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.

Bioworld Molecular Weight: ~ 33 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: ADP/ATP translocase 3; ADP,ATP carrier protein 3; ADP,ATP carrier protein, isoform T2; ANT 2; Adenine nucleotide translocator 3; ANT 3; Solute carrier family 25 member 6; SLC25A6; ANT3; ORF Names: CDABP0051

Immunogen: Synthetic peptide, corresponding to amino acids 120-160 of Human SLC25A6.

Conjugate: Unconjugated

Modification: Unmodified