Product Description

SLC25A6 (R155) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS3799-50, BS3799-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: ANT2 (adenine nucleotide translocator 2), also known as SLC25A5 (solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5), T2, T3, 2F1 or AAC2, is a 298 amino acid mμlti-pass membrane protein that localizes to the inner mitochondrial membrane and contains three solcar repeats. Existing as one of the most abundant mitochondrial proteins, ANT2 functions as a homodimer that facilitates the exchange of ADP and ATP between the mitochondrion and the cytosol, thus linking the compartment of ATP production (within the mitochondrion) to the areas of ATP utilization (within the cytosol). Suppression of ANT2 in breast cancer cells resμlts in apoptosis and tumor growth inhibition, suggesting that ANT2 may be involved in carcinogenesis. ANT3 (adenine nucleotide translocator 2) is a 298 amino acid mitochondrial protein that functions in a similar manner to ANT2 but, unlike ANT2, may also play a role in the formation of the permeability transition pore complex (PTPC), a structure that is important for the regμlation of apoptosis.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: ADP/ATP translocase 3, ADP, ATP carrier protein 3, ADP, ATP carrier protein, isoform T2, ANT 2, Adenine nucleotide translocator 3, ANT 3, Solute carrier family 25 member 6, SLC25A6, ANT3, ORF Names: CDABP0051

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 120-160 of Human SLC25A6.

Dilution: WB: 1:500~1:1000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: SLC25A6 (R155) polyclonal antibody detects endogenous levels of SLC25A6 protein.

Molecular Weight: ~ 33 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P12236

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only