SLC39A7 Polyclonal Antibody-BS5979

SLC39A7 Polyclonal Antibody

Catalogue Numbers: BS5979-50, BS5979-100

Sizes: 50µl, 100µl

Alternative Name: Zinc transporter SLC39A7; Histidine-rich membrane protein Ke4; Really interesting new gene 5 protein; Solute carrier family 39 member 7; Zrt-, Irt-like protein 7; ZIP7; HKE4; RING5

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q92504

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB ICC

All Applications: WB: 1:500~1:1000
ICC: 1:50~1:200

Background: Zinc is an essential cofactor that is involved in cell growth and development, as well as in protein, nucleic acid and lipid metabolism. The transport of zinc across the cell membrane is crucial for correct enzyme and overall cell function. ZIP7, also known as SLC39A7 (solute carrier family 39 (zinc transporter), member 7), KE4, HKE4, RING5 or H2-KE4, is a 469 amino acid multi-pass membrane protein that belongs to the ZIP transporter family. Expressed at high levels in kidney, placenta, pancreas and lung, ZIP7 functions as a zinc transporter that facilitates the movement of zinc, both from the extracellular environment and from intracellular storage compartments, to the cytosol. The gene encoding ZIP7 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SLC39A7 polyclonal antibody detects endogenous levels of SLC39A7 protein.

Bioworld Molecular Weight: ~ 50 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of SLC39A7 polyclonal antibody at 1:500 dilution
Lane 1: Hela cell lysate
Lane 2: sp2/0 cell lysate
Lane 3: H9C2 cell lysate

Immunogen: Synthetic peptide, corresponding to amino acids 179-224 of Human SLC39A7.

Conjugate: Unconjugated

Modification: Unmodified