SLIT2 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-13664-60, E-AB-13664-120, E-AB-13664-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: SLIT2
Target Synonym: Drad 1; E030015M03Rik; E130320P19Rik; FLJ14420; OTTHUMP00000158695; OTTHUMP00000217852; OTTHUMP00000217853; OTTHUMP00000217854; Slil 3; Slil3; Slit 2; Slit homolog 2 (Drosophila); Slit homolog 2; Slit homolog 2 protein; Slit homolog 2 protein C-product; Slit-2; Slit2; SLIT2
Research Areas: Cancer, Neuroscience
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: O94813
Background: Secreted leucine-rich repeat-containing proteins 1-3 (Slit1-3) are secreted glycoproteins that influence axonal guidance and mediate normal neural development by acting as high-affinity signaling ligands for the repulsive guidance receptor, Roundabout (Robo. Within the developing central nervous system (CNS) of different vertebrate systems, Slit proteins are expressed in equivalent regions, suggesting a conserved function among vertebrate homologs. Slit is expressed in the midline of the central nervous system in both vertebrates and invertebrates, where it functions as a regulatory factor of mesodermal cell movement during gastrulation. Slit2 is a short range inhibitory guidance cue for retinal ganglion cell (RGC) axons that may mediate spatial progression of RGCs.
Concentration: 0.3 mg/mL
Immunogen: Synthetic peptide of human SLIT2
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:25-1:100
Calculated MW: 170kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only