Product Description

Smad3 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11609-50, MB11609-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P84022

Host: Rabbit

Reactivity: Human, Mouse, Rat, Hamster

Applications: WB, IP,

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: Smad3 transcription factor phosphorylated and activated by TGF-beta-type receptors. A receptor-regulated Smad (R-smad). Binds directly to consensus DNA-binding elements in the promoters of target genes. In mouse required for establishemnt of the mucosal immune response and proper development of skeleton.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 48 kDa; Observed MW: 52 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Smad3 in 3T3, C6 lysates using Smad3 antibody., Western blot analysis of Smad3 in Jurkat lysates using Smad3 antibody., Western blot analysis of Smad3 in K562, CHO-K1 lysates using Smad3 antibody

Alternative Name: SMAD3; MADH3; Mothers against decapentaplegic homolog 3; MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; JV15-2; SMAD family member 3; SMAD 3; Smad3; hSMAD3

Immunogen: Recombinant protein of human Smad3

Conjugate: Unconjugated

Modification: Unmodified