Smad3 (Phospho-Ser423/425) Rabbit Polyclonal Antibody - BT-AP12684

Smad3 (Phospho-Ser423/425) Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP12684-20, BT-AP12684-50, BT-AP12684-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene belongs to the SMAD| a family of proteins similar to the gene products of the Drosophila gene andapos;mothers against decapentaplegicandapos; (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

Research Areas: Epigenetics and nuclear signaling; Signal transduction; Metabolism; Cancer; Stem cells

Target Protein: SMAD3

Applications: WB

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Smad3

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P84022; Mouse: Q8BUN5; Rat: P84025

Synonyms: Smad3;Ser423/425; Mothers against decapentaplegic homolog 3; MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; JV15-2; SMAD family member 3; SMAD 3; Smad3; hSMAD3

GeneID: Human: 4088; Mouse: 17127; Rat: 25631

Research Use Only