SMC3 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A18402-20, A18402-100
Citations, Manuals and MSDS Available upon request.
Background: This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein.
Category: Polyclonal Antibodies
Applications: WB, IP, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 142kDa
Observed Molecular Weight: 142kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 9126
SWISS: Q9UQE7
Alternate Names: BAM; BMH; HCAP; CDLS3; CSPG6; SMC3L1; SMC3
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IP, 0.5μg-4μg antibody for 400μg-600μg extracts of whole cells ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, DNA Damage Repair, Cancer, ATM Signaling Pathway, Cell Biology Developmental Biology, Apoptosis, Cell Cycle.
NCBI Alias: SMC3
Research Use Only