Product Description

SMC6 Polyclonal Antibody

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Sizes: 50µl, 100µl

Catalogue Numbers: BS65989-50, BS65989-100

Swiss-Prot: Q96SB8

Host: Rabbit

SMC6 Polyclonal Antibody-BS65989

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,

Applications: IHC-P

All Applications: IHC-P=1:100-500

Background: SMC5/6 complex is recruited to nuclease induced double strand breaks (DSBs) and is required for the recruitment of cohesin to DSBs. The human SMC5/6 complex and the SUMO ligase activity of hMMS21 are required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells.

Purification and Purity: affinity purified by Protein A

Specificity: SMC6 Polyclonal Antibody detects endogenous levels of SMC6 protein.

Bioworld Molecular Weight: 126 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Paraformaldehyde-fixed, paraffin embedded (rat stomach)Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SMC6) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C,, Paraformaldehyde-fixed, paraffin embedded (rat lung)Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SMC6) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C

Alternative Name: SMC6L1; SMC 6; SMC6; SMC6 protein; SMC6 structural maintenance of chromosomes 6 like 1; Structural maintenance of chromosomes 6; Structural maintenance of chromosomes 6 like 1; Structural maintenance of chromosomes protein 6.

Immunogen: KLH conjugated synthetic peptide derived from human SMC6:155-260/1091

Modification: Unmodified

Conjugate: Unconjugated