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SMIF Polyclonal Antibody - BT-AP08408

SMIF Polyclonal Antibody - BT-AP08408

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SMIF Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP08408-20, BT-AP08408-50, BT-AP08408-100

Citations, Manuals and MSDS Available upon request.

Background: Decapping is a key step in general and regulated mRNA decay. mRNA-decapping enzyme 1A encoded by DCP1A is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway. Alternative splicing of this gene results in multiple transcript variants.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: DCP1A

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: SMIF Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 63278

UniProt Accession: Human: Q9NPI6; Mouse: Q91YD3

Synonyms: DCP1A; SMIF; mRNA-decapping enzyme 1A; Smad4-interacting transcriptional co-activator; Transcription factor SMIF

GeneID: Human: 55802; Mouse: 75901

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