Product Description

SMPD1 / ASM Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-67785-60, E-AB-67785-120, E-AB-67785-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: SMPD1 / ASM

Target Synonym: SMPD1; ASM; ASMASE; NPD; SMPD1/ASM

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P17405

Background: The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified.

Concentration: 1 mg/mL

Immunogen: Recombinant fusion protein of human SMPD1 / ASM

Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IF 1:10-1:100

Calculated MW: 63kDa/64kDa/69kDa

Observed MW: 55KDa/70KDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only